Rose Hips supplements health benefits by Ray Sahelian, M.D.
December 23 2016

Rose hips develop from blossoms of the wild rose (rosa canina) and are a popular natural remedy. Laboratory experiments have shown that rose hip extract inhibits lipid oxidation. Rose hips contain many flavonoids that act as antioxidants.

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MultiVit Rx - High Quality Daily Vitamins and Minerals with Ascorbic Acid and Rose Hips - 500 mg

Rose Hips are round red fruits found on natural roses. Rose hips are a great source of Vitamin C and bioflavonoids.

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This MultiVit Rx product has 500 mg of ascorbic acid and rose hips per daily dose.


Benefits of Rose Hips
In clinical studies serum CRP and creatinine levels declined in healthy subjects and patients with osteoarthritis under rose hip treatment. Additionally patients suffering from osteoarthritis reported that physical symptoms declined. Data from a randomised controlled trial indicate not only that pain significantly declined but also flexion of the hip improved in the active treatment group. The anti-inflammatory properties of rose hip are useful as a natural treatment in patients with osteoarthritis. It remains to be proven which of the components are responsible for these effects. There is some evidence that in addition to the high vitamin content flavonoids may be actively involved.

Arthritis and osteoarthritis benefit
A powder made from the fruit of a subspecies of dog rose (Rosa canina) seems to alleviate pain and stiffness in the knees, hips, and other joints. Researchers in Denmark gave 94 osteoarthritis patients either 5 g of the rose-hip powder daily or a placebo for three months. Then the groups switched powders for another three-month period. While taking the rose hip powder, patients reported a significant reduction in pain, disability, and stiffness. They also reported a marked decrease in the amount of pharmaceutical analgesics they took. The trial adds weight to a 2004 study in which people taking Litozin (a standardized powder of rose hip that’s available without a prescription in the US) also improved their osteoarthritis symptoms.

Osteoarthritis Cartilage. 2008. Does the hip powder of Rosa canina (rosehip) reduce pain in osteoarthritis patients?--a meta-analysis of randomized controlled trials. Meta-analysis of randomized controlled trials (RCTs)--of a hip powder of Rosa canina (rosehip) preparation for symptomatic treatment of osteoarthritis (OA), in order to estimate the empirical efficacy as a pain reducing compound. Although based on a sparse amount of data, the results of the present meta-analysis indicate that rosehip powder does reduce pain; accordingly it may be of interest as a nutraceutical, although its efficacy and safety need evaluation and independent replication in a future large-scale/long-term trial.

A powder made from seeds and shells of a rose-hip subspecies (Rosa canina) reduces symptoms of knee and hip osteoarthritis: a randomized, double-blind, placebo-controlled clinical trial.
Scand J Rheumatol. 2005. Department of Clinical Biochemistry, Copenhagen County Hospital Gentofte, Hellerup, Denmark.
The aim of this study was to determine whether a herbal remedy made from a subspecies of rose-hip (Rosa canina) might reduce symptoms of osteoarthritis and consumption of rescue medication in patients suffering from osteoarthritis. Ninety-four patients with osteoarthritis of the hip or knee were enrolled in a randomized, placebo-controlled, double-blind crossover trial. Forty-seven patients were given 5 g of the rosehip herbal remedy daily for a period of 3 months and the remaining patients were given a similar amount of placebo. The group initially treated with placebo was then changed to rose-hip and vice versa for another 3-month period. Rose-hip resulted in a significant reduction in WOMAC pain as compared to placebo, when testing after 3 weeks of treatment. The consumption of 'rescue medication' significantly declined as a result of active treatment. WOMAC disability, stiffness, and global assessment of severity of the disease were not altered by 3 weeks but decreased significantly after 3 months of treatment. The data suggest that the present rosehip herbal remedy can alleviate symptoms of osteoarthritis and reduce the consumption of 'rescue medication'.

Prevention magazine had an article concerning ROSE HIPS from the "rosa canina" which contains glycosides and may be of benefit in arthritis. My wife has pain in her hands due to arthritis.

You have, no doubt, seen the report (now appearing in newspapers here in the U.K.) about the efficacy of rose hips in regard to pain alleviation for arthritis sufferers. Have you any opinion on the research?
   There's been very little research regarding rose hips and arthritis, but much more with other nutrients, so for the time being glucosamine, chondroitin, and other osteoarthritis nutrients are at the top of my list. However, combining rose hips and other nutrients and herbs may be a good option.

Celiac disease
I read a commentary regarding a study on rose hips and Celiac's disease, it said that many were cured after taking rose hips. I would love to know what to look for in purchasing this supplement and how much to take and how long. Thank you for a wonderful website, I am enthralled to get some truth, and not hype.
   I can't find any published human research regarding the use of this product for Celiac's disease.

Diabetes and heart disease
Eur J Clin Nutr. 2012. Effects of rose hip intake on risk markers of type 2 diabetes and cardiovascular disease: a randomized, double-blind, cross-over investigation in obese persons. In studies performed in mice, rose hip powder has been shown to both prevent and reverse high-fat diet-induced obesity and glucose intolerance as well as reduce plasma levels of cholesterol. The aim of this study was to investigate whether daily intake of rose hip powder over 6 weeks exerts beneficial metabolic effects in obese individuals. A total of 31 obese individuals with normal or impaired glucose tolerance were enrolled in a randomized, double-blind, cross-over study in which metabolic effects of daily intake of a rose hip powder drink over 6 weeks was compared with a control drink. Body weight, glucose tolerance, blood pressure, blood lipids and markers of inflammation were assessed in the subjects. In comparison with the control drink, 6 weeks of daily consumption of the rose hip drink resulted in a significant reduction of systolic blood pressure (-3.4%), total plasma cholesterol (-4.9%), low-density lipoprotein (LDL) cholesterol (-6.0%) and LDL/HDL ratio (-6.5%). The Reynolds risk assessment score for cardiovascular disease was decreased in the rose hip group compared with the control group (-17%). Body weight, diastolic blood pressure, glucose tolerance, and plasma levels of high-density lipoprotein (HDL) cholesterol, triglycerides, incretins and markers of inflammation did not differ between the two groups. Daily consumption of 40 g of rose hip powder for 6 weeks can significantly reduce cardiovascular risk in obese people through lowering of systolic blood pressure and plasma cholesterol levels.

Composition and substances in the plant
Rose hip extract contains polyphenols such as anthocyanins, i.e. cyanidin-3-O-glucoside, several glycosides of quercetin and glycosides of taxifolin and eriodictyol. Phloridzin was identified, and several conjugates of methyl gallate were also found, one of which was tentatively identified as methyl gallate-rutinoside. Catechin and quercetin were found as the aglycones in the extract. Carotenoids found in rose hips include beta-carotene, lycopene, beta-chryptoxanthin, rubixanthin, zeaxanthin and lutein. Of course, there is a lot of Vitamin C in rose hip.

Rose hips are available as rose hips oil and rose hip tea, along with rose hip supplements and mixed with other nutrients and herbs.

Skin health, aging, wrinkles
Clin Interv Aging. 2015. The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity. The effects of a rose hip powder Hyben Vital made from seeds and shells was evaluated on cell senescence, skin wrinkling, and aging. A total of 34 healthy subjects, aged 35-65 years, with wrinkles on the face (crow's-feet) were subjected to a randomized and double-blinded clinical study of the effects of the rose hip powder, as compared to astaxanthin, a well-known remedy against wrinkles. During the 8-week study, half of the participants ingested the standardized rose hip product, while the other half ingested astaxanthin. Objective measurements of facial wrinkles, skin moisture, and elasticity were made by using Visioscan, Corneometer, and Cutometer at the beginning of the study, after 4 weeks, and after 8 weeks. Evaluation of participant satisfaction of both supplements was assessed using questionnaires. In addition, the effect of the rose hip preparation on cell longevity was measured in terms of leakage of hemoglobin through red cell membranes (hemolytic index) in blood samples kept in a blood bank for 5 weeks. The rose hip group showed statistically significant improvements in crow's-feet wrinkles, skin moisture, and elasticity after 8 weeks of treatment. A similar improvement was observed for astaxanthin. Likewise, both groups expressed equal satisfaction with the results obtained in their self-assessment. The rose hip powder further resulted in increased cell longevity of erythrocyte cells during storage for 5 weeks in a blood bank. Results suggest that intake of the standardized rose hip powder Hyben Vital improves aging-induced skin conditions. The apparent stabilizing effects of the rose hip product on cell membranes of stored erythrocyte cells observed in this study may contribute to improve the cell longevity and obstructing skin aging.

Rose Hip study and research
Minerva Ginecol. 2013. Lady Prelox improves sexual function in generally healthy women of reproductive age. This supplement study evaluates the Female Sexual Function Index (FSFI) of 100 healthy women (37 to 45 years) with moderate sexual dysfunction who underwent a management program of lifestyle, diet, exercise, and stress control. In association with the management program a group of these women also used the supplement Lady Prelox in tablets (20 mg Pycnogenol pine bark extract, 200 mg L-arginine, 200 mg L-citrulline and 50 mg Rosvita ® rose hip extract) for eight weeks.

Effects of Rosa canina fruit extract on neutrophil respiratory burst.
Phytother Res. 2002.
Respiratory burst leads polymorphonuclear neutrophils (PMN) to produce reactive oxygen species (ROS) such as superoxide anions (O(2)(o-)), hypochlorous acid (HOCl) and hydrogen peroxide (H(2)O(2)) which may possess deleterious effects for the organism. Rosa canina fruits are well known to contain a large amount of vitamin C which is antioxidant. This study was focused on the polyphenolics contained in rose hips to evaluate their antioxidative properties. We prepared a rose hip extract deprived of vitamin C. The extract contained mainly phenolics such as proanthocyanidins and flavonoids. We investigated its effects directly against (O(2)(o-)), HOCl and H(2)O(2) and investigated its effects on isolated PMN. For that, in vitro inflammatory conditions were reproduced by stimulating PMN with stimuli having different transductional pathways, in order to determine a possible mechanism of action. The results showed that the extract can inhibit ROS tested in acellular and cellular systems. The extract did not present an effect on PMN metabolism. Therefore, the antioxidative effects of rose hipsare due not only to vitamin C but also to polyphenolics.

Rose hips: a new occupational allergen.
J Allergy Clin Immunol. 1990.
We evaluated 13 workers with respiratory symptoms apparently related to occupational exposure to powdered rose hips. Nine workers had asthma, five had rhinitis, and one worker had urticaria. Seven workers had evidence of IgE specific for rose hips based on positive skin prick tests and positive in vitro tests. We conclude that rose hips are occupational allergens capable of producing asthma.

A herbal remedy, Hyben Vital (standard powder of a subspecies of Rosa canina fruits), reduces pain and improves general wellbeing in patients with osteoarthritis--a double-blind, placebo-controlled, randomised trial.
Phytomedicine. 2004.
The treatment of osteoarthritis, a disease that eventually affects the majority of the older population, involves the alleviation of symptoms such as pain and stiffness, and the reduction of inflammation. The double-blind, placebo-controlled, crossover study reported here examined the effect of Hyben Vital, a herbal remedy made from a subtype of Rose hips and recently reported to have anti-inflammatory properties, on the symptoms of osteoarthritis. One hundred and twelve patients with osteoarthritis were randomly allocated to treatment with either Hyben Vital 5 g daily or an identical placebo for 3 months, followed immediately by the alternative treatment. The patients assessed changes in joint pain and stiffness after each treatment period on a 5-point categorical scale. General wellbeing, including mood, sleep quality and energy were also assessed and recorded in a personal diary. The results in the two arms of the crossover differed markedly. Group A (placebo first) showed significantly more improvement from Hyben Vital than from placebo, for pain and for stiffness. But Group B (Hyben Vital first) revealed a positive effect of the same order as for Hyben Vital in group A, not only from the active drug, but also from placebo (difference not significant). An identical pattern was observed when we evaluated general wellbeing from the diary records. When patients, on the basis of reduction in joint pain, were divided into responders and non-responders, the first 3 months of active treatment (group A) showed a response rate of 31/47 (66%) compared to that of placebo (group B) 18/50 (36%). No major side effects occurred in either group. The data indicate that Hyben Vital reduces the symptoms of osteoarthritis. We interpret the marked differences in the responses of the two groups as indicating a strong "carryover" effect of Hyben Vital.

Nutrient composition of rose seed and oils.
J Med Food. 2002.
Rose seeds were evaluated for weight of 100 seeds, moisture, crude protein, ash, crude oil, energy, and mineral content. Also, fatty acid composition was determined in the seed oils. The weight of 100 seeds, moisture, crude oil, energy, and iron (Fe) content of Ermenek rose seeds were found to be higher than those of other regions. The major fatty acids identified by gas chromatography of rose seed oils growing wild in the Hadim, Taskent, and Ermenek regions in Turkey were, respectively, as follows: palmitic (3%, 1.7%, and 2%), stearic (2.4%, 2%, and 1.6%), oleic (16.7%, 18.4%, and 14%), linoleic (54%, 51%, and 48%), linolenic (17.1%, 16.4%, and 18%), and arachidic (2%, 1.8%, and 2.6%). The seeds were rich in oil and minerals. The oil may be valuable for food and other uses because of its high unsaturated content.

Roses are cherished for their unique beauty and captivating fragrance. The flower has come to represent the ideals of beauty and love, and the enchanting aroma of a rose evokes the warm relaxation of a midsummer's night or the playful softness of a spring morning. But despite the attractiveness of the flower, it's the hips of that beautiful rose that deserve the spotlight. Rosehips, the fruit of the rose plant, deliver a wealth of vitamin C, bioflavonoids, iron, and an array of nutrients vital for the health of our bodies. Throughout history, rosehips have been valued for their healthful properties. In fact, during World War II, the whole of England turned to rosehips for their vitamin C during a crippling citrus shortage.