Kola Nut side effect, weight loss, health benefit
March 22 2017 by
Ray Sahelian, M.D.

Kola Nut is the seed kernel of a large African tree grown commercially around the world. It's chief constituents are caffeine, theobromine, tannins and phenolics, kolatin, and kolanin. Kola nut has thermogenic and stimulant properties. Guarana and kola nut enjoy great popularity in their native lands because they are also rich in caffeine, which serves as a stimulant.

Weight Loss options to consider
5-HTP is a nutrient that helps curb appetite in some individuals. 5-HTP, by converting into serotonin, can be used temporarily to improve will power and decrease the urge to eat until more established weight loss habits are in place.
Acetyl-l-carnitine at a dose of 200 to 600 mg is a mind booster and antioxidant that can curb appetite in some people.For more information about Weight loss.

Pak J Biol Sci. 2013. Proximate and phytochemical of Cola nitida and Cola acuminata. The aim of the research was to examine Cola nitida and Cola acuminata for their phytochemical and proximate compositions. Presence of secondary metabolites do provide information about the plants for their potentials as a lead candidates for the novel drug discovery. The proximate analysis was done using the method of Association of Official Analytical Chemists (AOAC) and the phytochemical analysis was done using methods of Markkar and Goodchild for tannin, Brunner for saponin, Harbone for alkaloid and Bohm and Koupai-Abyazani for flavonoid. The proximate results showed that the moisture content of Cola acuminata and Cola nitida were in the range of 9%, ash 2%, fat 3%, protein 19%, crude fiber 7% and carbohydrate 58%. Cola acuminate has more protein content, ash and fat than Cola nitida. The result of phytochemical analysis showed that Cola acuminata has more alkaloids (2%), tannin (6%) and saponin (8%) than Cola nitida. The phenol contents of the two kola nuts were the same range 0.27%, the flavonoid were in the range of 0.12%.

Kola Nut Research
Herbal ephedra / caffeine for weight loss: a 6-month randomized safety and efficacy trial.
Boozer CN. St Luke's-Roosevelt Hospital and Columbia University, New York
Int J Obes Relat Metab Disord. 2002.
To examine long-term safety and efficacy for weight loss of an herbal Ma Huang and Kola nut supplement (90/192 mg/day ephedrine alkaloids/caffeine). Six-month randomized, double-blind placebo controlled trial. A total of 167 subjects (body mass index (BMI) 31 kg/m(2)) randomized to placebo or herbal treatment at two outpatient weight control research units. By last observation carried forward analysis, herbal vs placebo treatment decreased body weight, body fat and LDL-cholesterol, and increased HDL-cholesterol. Herbal treatment produced small changes in blood pressure variables, and increased heart rate, but cardiac arrhythmias were not increased. By self-report, dry mouth, heartburn, and insomnia were increased and diarrhea decreased. Irritability, nausea, chest pain and palpitations did not differ, nor did numbers of subjects who withdrew. In this 6-month placebo-controlled trial, herbal ephedra / caffeine kola nut (90/192 mg/day) promoted body weight and body fat reduction and improved blood lipids without significant adverse events.

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Q. I enjoy your website. I have a question about cortisol and Kola Nut. I have read and heard that a cup of coffee can raise your cortisol level (plus other factors as well, ex.: stress ect.) Is it the caffeine in the coffee that raises our cortisol level and if so, does the caffeine in Kola Nut and Guarana do the same. I haven't been able to find anything about this at all. I would appreciate any knowledge you have on this. My husband(53yrs) and I (52yrs)stopped drinking coffee and the odd time use Kola Nut. He likes to use it when he is competing in his swimming. We don't use alot, but I was wondering if it affects our cortisol level. ?
     A. It is difficult to say whether kola nut raises cortisol levels since there are hardly any human studies evaluating the role of kola nut tea or supplements on hormone levels.

Q. What is your opinion of taking a kola nut extract?
     A. I don't have any experience with kola nut extract.

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