Cipro antibiotic by Ray Sahelian, M.D.
April 6 2015

Cipro is an antibiotic. There is now a generic versions of Bayer Corporation Pharmaceutical Division's CIPRO I.V., a drug to treat certain bacterial infections. Bayer Pharmaceuticals introduced the first broad spectrum oral fluoroquinolone, Ciprofloxacin ( Cipro, Ciproxin ) in 1988.

Adverse effects, toxicity, caution, danger, side effects
J Am Podiatr Med Assoc. 2015. To cipro or not to cipro bilateral achilles ruptures with the use of quinolones. Ciprofloxacin and other fluoroquinolones are commonly used broad-spectrum antimicrobial agents for treating bacterial infections. This class of antibiotic drugs has uncommon adverse effects that include tendonitis, tendon ruptures, and other tendon abnormalities. We describe a patient with spontaneous bilateral complete Achilles tendon rupture after ciprofloxacin treatment. Surgical repair was performed successfully, and the patient completed physical rehabilitation without incident.

Cipro indications
Cipro has been approved for the treatment of 14 types of infections, especially urinary tract infections (UTIs) such as acute uncomplicated cystitis, pyelonephritis, and chronic bacterial prostatitis.

Cipro IV
The intravenous formulation of Cipro was introduced in 1991. Ciprofloxacin Injection, USP, is indicated for the treatment of infections, including urinary tract infections, lower respiratory tract infections (including pneumonias in hospitalized patients, nosocomial pneumonia), bone and joint infections, complicated intraabdominal infections, skin and skin structure infections, and therapy of patients with fever and neutropenia.
   CIPRO I.V. Injection is on the top 200 list of highest-selling brand-name drugs in the United States. Ciprofloxacin Injection USP, 10 mg/ mL, is packaged in 20 mL, and 40 mL vials and a 120 mL pharmacy bulk package, respectively. These products are manufactured by multiple generic companies.