July 5, 2021

I Will Not Be Taking the Current Vaccines

After being in the "hesitant" category for several months I am now in the "no" category. As a retired medical doctor I have plenty of time, and a genuine fascination, to thoroughly research this topic. I have been diligently reviewing every scientific journal I can find, reading every online news article I come across, and going through countless case reports on the CDC VAERS website. I now have a clearer understanding of how these vaccines influence our immune system and organs, how they could be of benefit, and how they cause the multiple short, medium, and long term adverse effects.

I am convinced that the benefits promoted by experts on TV regarding these vaccines are less than what they promise, and the adverse reactions are more than they want us to believe. The effects of these vaccines on the human body are infinitely more complex than anyone can imagine... a million shades of gray, you may say.

From the Beginning
You just got injected with 0.3 ml of mRNA vaccine in your deltoid muscle. What happens next? The mRNA strands are enclosed in a bubble of lipid nanoparticles. This fluid will make its way into your bloodstream and the nanoparticles will travel throughout your body and enter platelets, the cells lining blood vessels, liver, adrenal glands, ovaries, bone marrow, intestines, brain, and other cells, tissues and organs (based on pharmacokinetic studies in animals provided by Pfizer and Moderna). A lot of it will also make its way into your lymphatic system, particularly the lymph nodes in your armpit where the immune cells produce antibodies. The immune cells in your nodes multiply and that is why some people notice swollen nodes in the armpit on the side of the injected arm. The mRNA bubbles will also go to your spleen.

Some of the circulating nanoparticles in the bloodstream will end up in the liver (distribution studies done in animals by Pfizer and Moderna). Once in the liver the nanoparticles enter your liver cells. There the mRNA strands instruct your liver cells to make the spike proteins (you can find images online) which are then released into your general circulation, further traveling through the rest of your body and then attaching or entering the cells of multiple tissues and organs. The spike proteins have a strong tendency to attach to ACE2 receptors on cells. A study published in Clinical Infectious Diseases, May 20, 2021, found spike proteins in the blood of volunteers who had their first Moderna shot. The mean peak level was 62 picograms per milliliter. This spike protein manufacturing process in your liver cells begins shortly after the shot and continues for a few days... and then the mRNA strands disintegrate. They don't keep making the spike proteins forever as some people claim, although they continue for a few more days in lymph nodes, spleen, and the deltoid muscle where you got the shot. The spike proteins that lodge in cells could stay there for weeks or months, or longer but eventually, similar to other foreign proteins, they should disentegrate and be disposed of by macrophages (although we do not have long-term animal study data whether some will linger on even longer). Once most or all are disposed of, will they leave behind irreperable damage to the cells, like battle scars? I want to thank my friend Ronik Khachatoorian, Ph.D., a brilliant molecular biologist, who has helped me better understand these complex processes. Ronik is an expert in the metabolic function of the liver, protein synthesis, immunology, and viruses -- he spent years studying dengue and zika viral reproduction. We chat on the phone several times a week but we still haven't figured out whether spike proteins are made in significant amounts in other tissues and organs of the body -- besides the liver, spleen, lymph nodes, and deltoid muscle (and probably bone marrow and ovaries). But even if small amounts are made in those places, and the spike proteins present themselves on the surface of cells, they could cause damage by themselves or initiate an immune reaction against them, causing additional damage. Ronik and I make a good team. I have a general medicine background which helps me see things from a broad, clinical perspective -- like the whole elephant -- and he helps me understand how things work at the cellular level. Ronik has calculated a rough estimate on how many spike proteins are made. He based this on the peak level of the spike proteins in the blood, their molecular weight, an estimate of each mRNA strand translating one spike protein every two minutes, that there are trillions of mRNA strands injected into the deltoid muscle, and that translation occurs for a week or so. The count could easily be a minimum of hundreds of trillions of spike proteins being made within that time frame. Of course this varies widely among individuals. The young with healthy livers and lymph nodes make much more than the elderly. It is impossible to know the exact numbers. We welcome other molecular biologists to offer their thoughts. You can find info about Ronik on LinkedIn.

Side Effects Explained
The immediate side effects that occur within minutes or up to an hour or two are probably due to the non-mRNA substances in the vaccine, such as PEG. These can cause allergic and anaphylactic reactions such as shortness of breath, elevated heart rate, swelling of the tongue or throat, etc. In some people this has led to ER visits, hospitalization, and death.

A Few Hours Later
Many people start noticing their reactions later in the evening or overnight. It takes a few hours for muscle cells, lymph nodes and the liver to produce the spike proteins in significant quantities which are then released in the bloodstream and travel to many places in the body. In the meantime the lymph glands and other parts of the immune system have just started making many types of inflammatory substances (such as cytokines) which, hours later, after being made in enough quantities, lead to a variety of symptoms such as fever, fatigue, malaise, headache, pain and redness at the injection site, and so on. Spike proteins could attach themselves to different cells and tissues, for instance muscle tissue, joints, heart, lungs, nerves, kidneys, intestines, brain, etc. Spike proteins by themselves can cause damage, and the outcome could be even worse if and when inflammatory substances recognize those cells as foreign and attack. This leads to muscle pain, joint pain, changes in heart rate, shortness of breath, ringing in the ears, dizziness or strange nerve sensations, and a host of symptoms that I discuss in detail -- along with my thoughts on spike protein shedding or transmission -- at Covid Vaccine Side Effects.

In some individuals the spike proteins may initiate blood clots. Spike proteins are thought to trigger platelets to clump together (platelet aggregation). Clots in our blood vessels can be tiny and not cause any problems and eventually dissolve; or, over time, grow big enough to travel to the brain causing a stroke, travel to the heart causing a heart attack, to the lungs causing pulmonary embolisms, form in blood vessels in the abdomen, or the clots can form in blood vessels in the legs causing a DVT, deep vein thrombosis. Sometimes they may be small and travel and lodge in different parts of our organs and not cause any noticeable effect (or mild, difficult to pinpoint symptoms), but nevertheless do minor damage to our organs. When the media mentions the "rare" cases of blood clots they do not acknowledge the possibility of countless small clots that go undetected. There could also be antibodies against platelets which could cause clot formation and/or a low platelet count leading to bleeding. AstraZeneca and Johnson and Johnson both have spike proteins on their viral vector which also trigger clots and, overall, cause similar adverse reactions. Keep in mind the possibility that not all batches of the vaccines are made perfectly. There could be some that have suboptimal numbers of mRNA strands, others may have more, and still others may have imperfect mRNA strands that translate spike proteins shaped differently than what we expect. This could have unknown consequences. I am also learning about spike proteins binding to ACE2 receptors on cells which are found predominanty in the cells lining the blood vessels, heart, lungs, kidneys, and intestines. I have recently learned that ACE2 receptors are also found on nerve cells in the brain and throughout the body which may explain the variety of nerve-related side effects people are experiencing (see the side effects page). Sometimes I wonder if a more appropriate name for an mRNA injection is SPEM, spike protein expressing material.

There are cases of delayed, or ongoing, immune responses such as skin rashes, hives, joint pains, cardiac and blood pressure problems, fatigue, and a variety of neurological issues that start a week or two later. I am now reading case reports of people having persistent health issues even three or four months post vaccine. Adverse reactions are often more intense after the second dose and having had a recent Covid-19 infection.

I am still in the process of understanding all the complex interactions that occur once a vaccine enters our body. For instance, spike proteins have a structure in some ways similar to certain proteins in our bodies. Our immune system, when recognizing these spike proteins, may form substances that attack similar looking proteins that are present on our cells; in some ways like an autoimmune reaction. This article is a work in progress and I frequently update it as I learn more. Trying to make sense of this complicated process is humbling. I am not sure if anyone on the planet completely understands in molecular detail what exactly is going on with these new vaccines in the body; and furthermore has connected the dots to the clinical signs and symptoms that certain vaccinated people are experiencing. I have a strong urge to solve at least part of the puzzle.

The Bottom Line
Please read my March 4 Facebook post to better understand my position, particularly in regards to the new variants (particularly Delta) which the current vaccines do not work well against.

Moderna and Pfizer vaccines, along with J&J, are not FDA approved, but allowed for emergency use only. Those who get the shots are part of a clinical trial that is not being statistically monitored. A large-scale medical intervention on hundreds of millions of people is being undertaken without the necessary research to meticulously determine the short- and long-term consequences. Vaccinated individuals are showing up at emergency rooms with a variety of signs and symptoms and we have not forewarned our already-overstressed doctors on how to manage such patients. Countless blood tests, CT scans, MRIs, and EKGs are being ordered at enormous expense to society. We basically have partially effective vaccines that were formulated last year before the new variants became predominant and nobody can tell us for certain how many months of necessary protection, on average, they provide. Is it four months, six months, eight months, or longer? If an elderly couple was vaccinated in January of this year, is it safe for them to gather indoors with their kids and grandchildren on July 4th? Or go safely on a cruise in August? People are getting infected, hospitalized, and dying even after receiving the two doses. These vaccines temporarily reduce but do not stop transmission of the virus from one person to the other and will require booster shots. Is it safe to keep getting these jabs over and over again every few months? About 10% of those who got the first shot did not return for the second. Was it because they had moderate or severe side effects, or died, or had a family member, co-worker, or friend with a serious reaction? The damage to the body after repeated shots will be worse. I wonder what percent of the fully vaccinated will opt out of the upcoming booster shot in the fall. Could frequent vaccination dysregulate the immune system? Trigger autoimmune conditions? Cause neurodegenerative conditions? It is legitimate to ask such questions, science requires it. These rushed vaccines can have quite unpleasant and serious adverse effects and in a minority of cases cause long-lasting damage to the body -- especially to the nerves and cardiovascular system. I know of individuals who have had relentless tinnitus (ringing in the ears) that has not let up for months. If someone is injured the vaccine manufacturers are protected from lawsuits. A vaccine-harmed individual may be burdened with large medical bills if not well insured, and even though the government supposedly provides a vaccine injury fund, good luck trying to prove that a severe harm or death that occurred a week or a month or a year later was due to the vaccine. A 78-year-old woman in Southern California died within minutes after a shot and the local health authorities were not willing to attribute her death to the shot.

Herd Immunity?
The public who follows mainstream news has been sold a fairy tale. In order for a vaccine to have a chance at helping achieve herd immunity it should be very safe, prevent the vaccinated from transmitting the virus to others, and be at least 80% effective for a period lasting several years or a lifetime. The current ones fall signifcantly short of these standards, particularly against the delta variant which is now predominant. After each shot a small percentage will be harmed and not return for a booster. Progressively, over time, this will shrink the pool of the vaccinated and will leave a growing number whose bodies can no longer tolerate further insult. The polio vaccine provides lifelong immunity and hence this virus has been practically eradicated. These Covid-19 vaccines are, in many ways, similar to the flu vaccines. We have been giving flu shots for decades yet we are nowhere close to herd immunity. Is it possible imperfect vaccines -- partial benefit for a limited period -- could spur the Covid-19 virus into mutating to strains more resistant to vaccination... similar to weak antibiotics that spur the growth of mutated superbugs? It could happen; and if so, this attempt at mass immunization with rushed vaccines could end up being one of the biggest public health policy blunders ever. Furthermore, people believe that once they get the shots they are virtually protected for a year. These individuals will drop their guard and engage in unsafe activities that put them at a higher risk of catching and transmitting the virus than if they never got the shots and took adequate precautions. A study from New Zealand theorized the vaccinated could harbor the virus in their nose and pass it on to others easier since they may not have much symptoms initially whereas an unvaccinated person would notice some flu-like symptoms right away and self-quarantine. Therefore it is unfair, intellectually dishonest, and frankly not supported by scientific evidence to bully and blame the unvaccinated for failure to achieve herd immunity. Viruses will mutate in the unvaccinated, they will mutate in those who are immune compromised, they will mutate in the vaccinated, and they will continue to mutate unless we eradicate them completely which is not achievable anytime soon through the currently-implemented strategies. Tens of thousands of people in the United States die from the flu virus each year, yet the seasonal mutations are not blamed on those who forgo the annual flu shot. People who truly believe these current vaccines provide excellent protection should, by their logic, not be overly concerned being around others who choose to decline the needle. If the vaccines are effective as claimed, why is the WHO recommending masks to be worn indoors? Some of the highest vaccinated countries in the world -- for instance the United Kingdom, United Arab Emirates, Seychelles, Chile, and others -- have not been able to suppress the rate of new infections. What if they had applied part of their efforts towards narrowly-focused public health measures, the use of known, safe, and inexpensive medications, along with a campaign to promote overall health among their citizens through means I mention below... would the outcome have been different? It's a fair question.

Risk Reduction, Natural Options
I hope brilliant scientists find anti-viral medications that stop this virus dead in its tracks (there is hope). Ivermectin, FDA-approved as a medicine to treat parasites, has shown promise as a prevention and treatment against Covid-19. One wonders if its early adaption and promotion in 2020 might have saved lives. I don't have personal experience with it and do not know the proper dosage or frequency of use. Other meds with promise include hydroxychloroquine and budesonide. Frankly I had been skeptical about the benefits of ivermectin and hydroxychloroquine but I am now more open-minded. A healthy diet with fresh fruits and vegetables, foods high in probiotics, weight loss, blood sugar control, exercise (to improve lung capacity), deep sleep, smoking cessation, frequent outdoors air and sun exposure and/or vitamin D, perhaps additional vitamin C and quercetin, are all likely to reduce the overall inflammatory state of our body, and thus reduce the severity of a viral illness, whether vaccinated or not.

Please talk to your health care provider before you decide whether vaccination is appropriate in your own particular situation (although, sadly, few have been well-informed on this topic, through little fault of their own). A Covid-19 infection can sometimes be serious and fatal. A small percentage have long-lasting health issues. We all have different reasons for getting these shots, or deciding not to (at least for the time being). We should hold no judgment against anyone who has been vaccinated or who wants to wait for additional safety and efficacy studies. Or, perhaps, wait for an improved second generation vaccine that protects against the new variants and is safer.

I wish you all stay safe. In these challenging times let us all empathically support each other to make the best of our situation no matter what our opinions.

Note: I retired in 2018 and was traveling around the world when this pandemic started. Friends and family kept asking me about the benefits and safety of these vaccines and wanted an honest opinion, so I began to look into it. The deeper I delved, the more I wanted to solve the puzzle. I originally placed this article on my personal Facebook Ray Sahelian page and it had more than 1,500 shares. Then, without warning, on Sunday April 18 (my post originally was placed on March 17), I woke up to see that the page, with dozens of references to medical journal articles, had been deleted. So I moved it here (luckily a friend had copied the article and emailed it to me). I think this is a reasonable and well-thought-out article. I am not comforted that FB deleted it without giving any warnings or reasons other than it "violated community standards." Are scientists not allowed to voice opinions that diverge from the currently accepted and potentially politically motivated narrative, especially on a topic with such limited understanding? So I opened an additional account on MeWe where info is not censored. Feel free to Follow me on Facebook, or friend me on MeWe; there are groups that discuss Covid vaccine adverse reactions without censorship. The information below the line has not been updated since 2019.